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In the SURPASS program, gastrointestinal side effects associated with the use of tirzepatide were similar to those observed with semaglutide and GLP1-RA drugs in general, both in terms of frequency and duration [3]
Additionally, intensive support is typically required to ensure that members remain compliant with behavior changes for the long-term
It shifts melanin synthesis toward a lighter pigment called pheomelanin rather than the darker eumelanin, which is why many people notice a gradual brightening or evening of skin tone with consistent use
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